See your baseline.
Follow your changes.
Where each reading sits today
Clean-up & Rebuilding and Targeted Defense sit below their reference ranges.
This sampleReference range
Activation starts a response
-
Activation Level
Alarm, fever and cell-recruiting signals
Within
-
Targeted Defense
Signals that show threats to T cells and power up cell-killing
Below
-
Where the Fast Response Is Working
In the blood, or moving cells into tissue
Within
Resolution ends it
-
Resolution Level
Early feedback and calming signals
Within
-
Regulatory Cells & Repair Signals
Longer-acting restraint on the response
Within
-
Clean-up & Rebuilding
Clearing spent cells and the shift toward repair
Below
The reference range is where most people measured the same way sit. Within means similar to them at this sample; it is not a statement about health.
How each reading has moved
Since the previous sample, four readings moved and two stayed about the same.
Sample 5Earlier samplesReference range
-
Activation Level
Moved down: now within, from at the upper edge.
-
Targeted Defense
Moved down: now below, from at the upper edge.
-
Where the Fast Response Is Working
Moved toward tissue: now within, from outside.
-
Resolution Level
About the same: now within, from above.
-
Regulatory Cells & Repair Signals
About the same: now within, from below.
-
Clean-up & Rebuilding
Moved down: now below, from within.
Samples are numbered 1 to 5. A reading counts as moved only when its shift since the previous sample is larger than the usual variation between samples.
The pathways behind a reading
Clean-up & Rebuilding: below its range · moved down. Less clearing of spent cells and less shift toward repair than the reference group.
Sample 5Sample 4That pathway’s reference range
-
Calming Through Metabolism
Breaks down an amino acid in a way that quiets T cells.
Below
-
Repair-type Clean-up Cells
Clean-up cells shift from attack to repair and rebuilding.
Lower edge
-
Retiring Neutrophils
Spent neutrophils die on schedule and are removed.
Below
Each reading is a weighted summary of several pathways: groups of genes that work together on one job. This shows where a reading differs from the reference group, not how well that job is being done or why.
Your immune cell mix
The estimated share of each immune cell family in the sample.
Sample 5Reference group, middle value
-
T cells
Sample 5: 27%Reference group: 34%
-
B cells
Sample 5: 6%Reference group: 7%
-
Killer cells
Sample 5: 4%Reference group: 3%
-
Dendritic cells
Sample 5: 0%Reference group: no reference value yet
-
Monocytes
Sample 5: 1%Reference group: no reference value yet
-
Neutrophils and related cells
Sample 5: 62%Reference group: 57%
Estimated from RNA, which is a different measurement from a blood count. Filled bars show Sample 5, with colors identifying cell families; lines show the reference group’s middle value. Dendritic cells and monocytes have no reference value yet.
- Activation starts a response
- Three readings follow the signals that raise the alarm and call in immune cells.
- Resolution ends it
- Three readings follow the signals that calm the alarm, clear away spent cells and begin repair.
- Immune cell mix
- An estimate, made from RNA, of the share of each kind of immune cell in your sample.
Each reading is placed against a reference group: people whose blood was measured the same way. Your report shows whether you are within the reference range, below it, above it, or at its edge. From your second sample, it also shows what moved.
Why isn't there one overall score?
Your inflammation system does several jobs, and they don't rise and fall together. A single score would average them, so two people with very different results could get the same number. Six readings keep the parts separate. A score also invites a grade, and a result here is a position, never a grade.
Why is it called the Inflammation Compass?
Navigators need to know two things: where they are, and which way they're moving. The Inflammation Compass gives you both for your inflammation. Your Bearing shows where your readings sit today. Your Course shows how far each has moved since your earlier samples, and Your Map plots the path you've taken. Where you go from there is your decision.
A different layer
of inflammation.
The most common inflammation test, hs-CRP, measures how much of one protein is in your blood. That protein is a stand-in for inflammation, and it has limits. It rises for many reasons, it shifts with age, weight, and smoking, and it can't show which part of your inflammation system is involved. The Inflammation Compass reads the system itself: which genes your immune cells are using, from the signals that start a response to the signals that end it. It adds to tests such as hs-CRP and doesn't replace them.
Compare what different tests measure
How our test fits your plan
Responses to these interventions are still being studied. This test does not establish whether a protocol caused a change.
From your home
to the laboratory.
Register your kit, complete consent and intake, then request your at-home blood collection. A phlebotomist confirms the time with you.
Biomeme Labs sequences your sample at its CLIA-certified laboratory in Philadelphia. Your PDF report is expected about one month after laboratory receipt.
The full collection processCommon questions.
Is it covered by insurance?
No. The Inflammation Compass is a direct-purchase wellness test and isn't billed to insurance. $389 per test, or $365 each when you order 4 or more. Mobile phlebotomy and shipping included.
Do I need a doctor's order?
No. You will be able to order without a prescription or doctor's order. Your report includes a version for your clinician, and we encourage you to review your results with them.
Is it available in my state?
At-home testing will be available in all US states except New York.
Is one sample useful, or do I need several?
One sample is useful by itself: it shows where each of your readings sits against the reference group, and it starts your baseline. A second sample gives you a comparison, so you can see what moved and by how much. From the third, a trend begins to show, and you can start to tell a passing shift from a pattern. Your report names the window for your next sample.
I've already started a supplement or a new routine. Is it too late?
No. Your first sample becomes your baseline from that point on. It can't show what changed before you gave it, so it won't tell you what the supplement or routine has already done. It will show where you stand now, and later samples will show what moves from here, including after you change, pause, or add something.
Is this a DNA test?
No. Think of your DNA as a fixed set of instructions you carry from birth. At any moment, each cell is using only some of them. When a cell uses a gene, it makes working copies of it, called RNA. A DNA test reads the instructions themselves. The Inflammation Compass counts the working copies in your immune cells, so it shows which instructions were in use when your sample was taken. That is why your results can change from one sample to the next, and why this test says nothing about your ancestry or about conditions you may have inherited.
What the test
cannot tell you.
This is a wellness test. It doesn't diagnose, rule out, or predict any disease, or determine whether a treatment is safe or effective. It is not cleared or approved by the U.S. FDA.
It shows what was measured in your blood at one moment, and it can't show what caused a result or a change, or where in your body inflammation is taking place. A reading within its range means you are similar to the reference group, which is not a statement about your health. Your immune cell mix is an estimate made from RNA and doesn't replace a blood count.
The gene sets draw on published research. Their response to training, sleep, GLP-1 medications and other interventions has not yet been demonstrated for this test.
Production & studio partners tested during COVID-19
Biomeme Labs provided molecular testing for these organizations during COVID-19.
Establish your baseline.
Reserve your spot for Inflammation Compass testing.
$389 per test, or $365 each when you order 4 or more. Mobile phlebotomy and shipping included.